Effect of Drug Resistance on the Pathogenicity and Virulence of Salmonella Typhimurium

Various strains of E. coli. and Salmonella typhimurium were studied in vitro for the presence plasmids controlling haemolysin, drug resistance, serum resistance colonization factor etc. They also tested mice to determine probable role on host pathogenicity. To effect associated R-factor pathogenicity virulence S. typhimurium, antibiotic sensitive resistant mice. The experiments showed that enhance lethality their host. This causes a serious problem effective treatment patient suffering with coli infections.